Asian Journal
Of Traditional Medicines

Abstract: Twenty-eight compounds, including flavones (2, 4-5, 7-11), flavonols (1, 3, 6, 21, 22), flavanones (12-18), isoflavones (19, 20), chalcones (23, 24), phenylpropanoids (25, 26), and others (27, 28) were isolated from the ethanol extract of the seeds of Pongamia pinnata (L.) Pierre and identified on the basis of physic-chemical constants and spectral analysis (NMR, ECD, [α]2 0 D ). Among them, compounds 16, 18, 21, 23, 25 and 26 were obtained from the genus for the first time. The cytotoxicities of the purified flavonoids against H292 cells were evaluated using MTT assays. As a result, compounds 14 and 15 displayed moderate cytotoxicities.

Key words: Pongamia pinnata (L.) Pierre, constituent, flavonoids, cytotoxicities