Antimicrobial activity and reversal of dexamethasone depressed healing by roots of Ficus racemosa L.

›› 2011, Vol. 6 ›› Issue (5): 224-230.

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Antimicrobial activity and reversal of dexamethasone depressed healing by roots of Ficus racemosa L.

Krishna Murti ¹*, Upendra Kumar ², Raghuvir Singh ³

1. Department of Pharmacology, Singhania University, Jhunjhunu, Rajasthan 333515, India 2. Department of Pharmaceutical Chemistry, College of Pharmacy, Azamgarh, Uttar Pradesh 276136, India 3. Department of Pharmaceutics, PDM School of Pharmacy, Safidon, Jind, Haryana 126112, India

Received:2011-09-15 Revised:2011-10-30 Online:2011-10-20 Published:2011-10-20
Contact: Krishna Murti

Abstract

Abstract: This study was conducted to evaluate aqueous & ethanolic extracts of Ficus racemosa for antibacterial and wound healing properties in presence of dexamethasone depressed healing conditions. Antibacterial properties of the extracts were studied against Klebsiella pneumoniae, Staphylococcus aureus and Escherichia coli bacterial strains, using the well diffusion method. Reversal mechanism of dexamethasone depressed wound healing properties by Ficus racemosa was determined using the incision and excision wound model. Extract of Ficus racemosa inhibited growth of all the test bacterial strains. Both the extract reverted the dexamethasone depressed healing effectively when compared with dexamethasone treated group. The results were comparatively significant (P< 0.05).

Key words: Ficus racemosa, wound healing, dexamethasone, antimicrobial activity, incision, excision wound model.

Krishna Murti *;Upendra Kumar;Raghuvir Singh . Antimicrobial activity and reversal of dexamethasone depressed healing by roots of Ficus racemosa L.[J]. , 2011, 6(5): 224-230.

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Antimicrobial activity and reversal of dexamethasone depressed healing by roots of Ficus racemosa L.

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Antimicrobial activity and reversal of dexamethasone depressed healing by roots of Ficus racemosa L.

Knowledge

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Cite this article

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References

Related Articles 8

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Asian Journal
Of Traditional Medicines