Asian Journal
Of Traditional Medicines

Abstract: Lomatogonium rotatum is rich in xanthones and flavonols but there are no literature reports of its quantitative analysis. Methanolic extracts of L. rotutum were analysed by HPLC luteolin-7-O-glucoside, apigenin-7-O-glucoside, luteolin, pigenin, 1, 3, 8-trihydroxy-4, 7-dimethoxyxanthone, 1, 4, 8-trihydroxy-5, 6-dimethoxyxanthone, 8-hydroxy-1, 3, 5-trimethoxyxanthone, 1-hydroxy-3, 4, 5-trimethoxyxanthone, 1-hydroxy-3, 5, 8-trimethoxyxanthone, 1-hydroxy-3, 7, 8-trimethoxyxanthone were quantified. The limits of quantification of these constituents were 0.32 %, 0.37 %, 0.13 %, 0.15 %, 0.25 %, 0.22 %, 0.39 %, 0.31 %, 0.12 % and 0.05 %, respectively, in the plant material. The HPLC method for analyzing the constituents can be used to evaluate the quality of L. rotatum.

Key words: Lomatogonium rotatum, xanthones, flavonoids, HPLC, quantitative analysis