亚洲传统医药 ›› 2020, Vol. 15 ›› Issue (6): 320-327.

• Regular Article • 上一篇    下一篇

Studies on chemical constituents of Ailanthus altissima (Mill.) Swingle and their antioxidant activity

Wanyi Shi, Yuxi Wang, Zhiyang Yan, Xiaoxiao Huang*   

  1. Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Liaoning Province, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China
  • 收稿日期:2020-03-04 接受日期:2020-07-01 出版日期:2020-12-20 发布日期:2020-12-23

Studies on chemical constituents of Ailanthus altissima (Mill.) Swingle and their antioxidant activity

Wanyi Shi, Yuxi Wang, Zhiyang Yan, Xiaoxiao Huang*   

  1. Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Liaoning Province, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China
  • Received:2020-03-04 Accepted:2020-07-01 Online:2020-12-20 Published:2020-12-23
  • Contact: School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, 103 Wenhua Rd., Shenyang 110016, China; Tel.: +86-24-43520793; E-mail: xiaoxiao270@163.com. E-mail:xiaoxiao270@163.com

摘要: Ailanthus altissima (Mill.) Swingle is a deciduous tree belonging to the Simaroubaceae family. The root and stem bark are traditional medicines for treating many diseases, such as diarrhea, dreaminess and intestinal tract bleeding. Phytochemical investigation of Ailanthus altissima (Mill.) Swingle led to the isolation of eight compounds. Chemical structures of these compounds were identified by analyzing their NMR spectroscopic data. Among them, compounds 1, 4, 5, 6 and 8 were isolated from Ailanthus Desf. for the first time. The antioxidant activities of these compounds were determined by DPPH radical scavenging method.

关键词: Ailanthus altissima (Mill.) Swingle, lignans, phenylpropanoids, antioxidant activity

Abstract: Ailanthus altissima (Mill.) Swingle is a deciduous tree belonging to the Simaroubaceae family. The root and stem bark are traditional medicines for treating many diseases, such as diarrhea, dreaminess and intestinal tract bleeding. Phytochemical investigation of Ailanthus altissima (Mill.) Swingle led to the isolation of eight compounds. Chemical structures of these compounds were identified by analyzing their NMR spectroscopic data. Among them, compounds 1, 4, 5, 6 and 8 were isolated from Ailanthus Desf. for the first time. The antioxidant activities of these compounds were determined by DPPH radical scavenging method.

Key words: Ailanthus altissima (Mill.) Swingle, lignans, phenylpropanoids, antioxidant activity