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本期目录

    2025年, 第20卷, 第1期 刊出日期:2025-02-28 上一期   
    The mechanism analysis of KangBingDuKouFuYe in treating throat infection based on network pharmacology and molecular docking
    Ying Long# , Xinhui Yang# , Hongfei Lv, Zhenyu Liu, Tianjun Guo, Chaohui Yang, Hui Liu, Qijia Yang, Xin Wu
    2025 (1):  1-13. 
    摘要 ( 66 )   PDF(14358KB) ( 27 )  
    KangBingDuKouFuYe (KBDKFY) is widely used to treat inffuenza, upper respiratory tract infections, mumps and other diseases. Due to their diverse active ingredients, it is believed that they may have excellent anti-inflammatory, antibacterial and antiviral effects. Therefore, we believe they may have multiple therapeutic targets for throat inflammation caused by bacterial or viral infections. This study utilizes network pharmacology methods to analyze the therapeutic effects of KBDKFY on Bacterial Pharyngeal Tonsillitis and Viral Pharyngitis, aiming to identify its active ingredients, action targets and related pathways through molecular docking. Additionally, it determines the afffnity between the main active ingredient and the core target before conducting in vitro bacteriostatic tests. The analysis results show that KBDKFY contains multiple active ingredients and potential targets for treating Bacterial Pharyngeal Tonsillitis and Viral Pharyngitis. KEGG enrichment analysis indicates that KBDKFY may have therapeutic effects on these conditions through pathways such as pathways in cancer, Kaposi sarcoma-associated herpesvirus infection, PI3K-Akt signaling pathway, and others. This provides a theoretical basis for further exploring pharmacological effects and clinical applications of KBDKFY.
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    Chemical composition and biological activities of Lysimachia capillipes Hemsl
    Ran Guo, Ruoming Li, Xiaomeng Zhang, Wenhan Wang, Yao Zhao, Yu Chen
    2025 (1):  14-29. 
    摘要 ( 31 )   PDF(5618KB) ( 24 )  
    Lysimachia capillipes (L. capillipes) Hemsl, belong to primulaceae pearl vegetables genus, is a treasure in traditional Chinese medicine. It has the effects of invigorating qi and tonifying deffciency, dispelling wind and activating blood, awakening the brain, relieving cough and regulating menstruation. With the development of modern medicine, the active components and therapeutic mechanisms of L. capillipes Hemsl have been gradually revealed. The present report systematically reviews the chemical composition and biological activities of L. capillipes Hemsl, to provide scientiffc basis and reference for detailed research on L. capillipes Hemsl.
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    Research progress of different kinds of traditional Chinese medicine in the treatment of type 2 diabetes
    Yuzheng Xiang, Xiaomeng Zhang, Ruoming Li, Wenhan Wang, Yao Zhao, Yu Chen
    2025 (1):  30-42. 
    摘要 ( 29 )   PDF(17418KB) ( 18 )  
    In recent years, diabetes has posed a serious threat to human health. Traditional Chinese medicine for lowering blood sugar has attracted much attention due to its unique advantages in the treatment of diabetes. This paper summarizes the research results on common traditional Chinese medicines for lowering blood sugar in recent years. These results lay a theoretical foundation for the future clinical development and use of hypoglycemic Chinese medicine, the improvement of the quality standards of hypoglycemic Chinese medicine, and the in-depth research on the mechanisms.
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