摘要：
Metabonomics, a key aspect of systems biology, offers novel approaches for early diagnosis, pharmacotherapy, and health management in Traditional Chinese Medicine (TCM). This paper summarizes its applications in establishing TCM quality standards, exploring material basis, clarifying mechanism, and assessing toxicity. By profiling TCM and its metabolites, metabonomics comprehensively captures chemical traits, enhancing quality evaluation precision. It also tracks metabolic dynamics to understand TCM’s absorption, distribution, metabolism, excretion, thereby facilitating the identification of active components and their underlying mechanisms. In toxicity assessment, metabonomics uncovers hepatic and renal toxicity while elucidating potential mechanisms. In summary, metabonomics fosters TCM modernization and globalization, serving as a pivotal tool for advancing research and development.
Ruiqi Ma, Rui Liu, Yuzheng Xiang, Yibo Wang, Ran Guo, Ying Li, Yu Chen. Applications of metabonomics in traditional Chinese medicine[J]. 亚洲传统医药, 2025, 20(3): 121-129.
Ruiqi Ma, Rui Liu, Yuzheng Xiang, Yibo Wang, Ran Guo, Ying Li, Yu Chen. Applications of metabonomics in traditional Chinese medicine[J]. Asian Journal of Traditional Medicines, 2025, 20(3): 121-129.
