亚洲传统医药
亚洲传统医药

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›› 2010, Vol. 5 ›› Issue (6): 212-218.

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Hepatoprotective and hepatocurative activity of the traditional medicine ketaki (Pandanus odoratissimus Roxb.) - An experimental evaluation

  

  • 收稿日期:2010-03-25 修回日期:2010-12-06 出版日期:2010-12-20 发布日期:2010-12-20

Hepatoprotective and hepatocurative activity of the traditional medicine ketaki (Pandanus odoratissimus Roxb.) - An experimental evaluation

Ilanchezhian R 1 *; Roshy Joseph. C 2
  

  1. 1. Department of Dravyaguna, Institute for Post Graduate Teaching & Research in Ayurveda, Gujarat Ayurved University, Jamnagar 361008, India; 2. Department of Rasashastra and Bhaishajya kalpana, Institute for Post Graduate Teaching & Research in Ayurveda, Gujarat Ayurved University, Jamnagar 361008, India
  • Received:2010-03-25 Revised:2010-12-06 Online:2010-12-20 Published:2010-12-20
  • Contact: Ilanchezhian R

Abstract: In developing countries like India, hepatic disorders are steadily increasing. Ketaki (Pandanus odoratissimus Roxb.), is an important traditional medicine used in northern Karnataka for jaundice. In the present study, the Watanabe and Takita (1973) experimental model was adopted to evaluate the hepatoprotective and hepatocurative activities of a Ketaki root decoction on CCl4–induced liver damage in albino rats. The degree of protective and curative activity was determined by measuring the levels of serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), alkaline phosphatase (ALP), total serum bilirubin and serum albumin. Histological studies were also carried out. The Ketaki root decoction was found to be hepatocurative but not hepatoprotective.

Key words: hepatoprotective, hepatocurative, yakrit, liver, ketaki, CCl4

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