亚洲传统医药

本期目录

2019年, 第14卷, 第5期　刊出日期：2019-10-20 上一期    下一期

Regular Article

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Network pharmacology-based screening of the active ingredients and potential targets of the genus of Croton for application to lung cancer Shaochun Shi, Yeqing Du, Chunxin Zou, Qingbo Liu, Shaojiang Song 2019 (5):  219-226.  摘要 ( 402 )   PDF(997KB) ( 444 )   Lung cancer has been the most common cancer in the world for several decades, and it was also the most common cause of death from cancer. Despite the several advances in the last few years into treatment of lung cancer, the survival remains extremely low. There is an urgent need to discover viable leads that can be developed into new clinically therapeutic drugs with good treatment effects. The analysis of current reported literatures suggest that natural products possess strong inhibitory efficacy against lung cancer. The plants of Croton genus belonging to Euphorbiaceae family, are widely used as herbal medicine in the folk. Which are reported to have abilities to treat several cancer cell lines especially lung cancer, a successive study was carried out to identify selective anticancer agents from these plants specie. Herein we employed a network pharmacological approach to understand its multi-therapeutics potentiality in Croton genus against lung cancer. In total, the database of the compound was established based on the methods of network pharmacology prediction and the compound-disease target network was constructed. We believed that our study would provide important clues for finding novel drug inhibitors for lung cancer. 相关文章 | 计量指标

Review

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Research review on the main chemical constituents and pharmacological properties of the leaves of Isatis indigotica Fortune Wei Hong, Yufei Xi, Weiyu Zhou, Xiaoxiao Huang, Shaojiang Song 2019 (5):  227-236.  摘要 ( 630 )   PDF(1236KB) ( 593 )   Isatis indigotica Fortune, belonging to Isatis genus of Cruciferae family, is widely used as a common Chinese herbal medicine in folk. As a traditional medicinal agent, a wide spectrum of chemical constituents have been isolated from the leaves, including alkaloids, flavonoids, flavonoid glycosides, organic acids and glycosides. The research shows that the leaves had multiple activities and good development prospect, which has attracted a wide range of attention. Hence, this article is presented as a review concentrating on chemical constituents and pharmacological activities of the leaves of I. indigotica Fort., aiming at supporting practical and useful information for the further research and development of this plant. 相关文章 | 计量指标

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Chemical constituents and pharmacological properties of Sarcandra glabra (Thunb.) Nakai. Hao Zhang, Peng Zhao, Yangyang Zhang, Xiaoxiao Huang, Shaojiang Song 2019 (5):  237-246.  摘要 ( 547 )   PDF(1414KB) ( 544 )   Sarcandra glabra (Thunb.) Nakai., belonging to Chloranthaceae genus of Sarcandra family, is widely used as the common Chinese herbal medicine in folk. As a traditional medicinal agent, a wide spectrum of chemical constituents have been isolated from the S.glabra, including sesquiterpenoids, triperpenoids, flavonoids, coumarins, phenolic acids and volatile oil. Modern pharmacological studies have shown that S.glabra has many biological activities such as anti-cancer, hepatoprotective activity, anti-inflammatory and anti-asthmatic activities. For the further development of this plant, the primary chemical constitutions of S.glabra and their activities have been summarized in this study. 相关文章 | 计量指标